Spirochetes Unwound

Blogging about those twisty bacteria known as spirochetes

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Monday, March 21, 2016

The genomes of 20 species of Leptospira

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A massive study describing the genomes of 20 species of Leptospira was published a few weeks ago in PLOS Neglected Tropical Diseases .  Th...
Thursday, February 11, 2016

How a new species of Lyme disease bacteria was discovered

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A new agent of the tick-borne illness known as Lyme disease has emerged in the upper Midwest.  The bacterium is genetically related to Borre...
Wednesday, November 11, 2015

Lighting up Leptospira interrogans to test antibiotic treatment of chronically-infected mice

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A group at the Pasteur Institute succeeded in generating a bioluminescent strain of Leptospira interrogans .  Their study was published las...
Sunday, September 6, 2015

Do Lyme disease spirochetes produce a toxin?

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According to the current view of Lyme disease pathogenesis, tissue damage is caused by the inflammatory response to the spirochetes.  Borrel...
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Monday, August 17, 2015

A biosignature of early Lyme disease

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Laboratory testing for Lyme disease involves two-tier antibody testing with sera from patients suspected of having the disease.  The first s...
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