Spirochetes Unwound
Blogging about those twisty bacteria known as spirochetes
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Sunday, September 15, 2013
Is sterilizing immunity against
Leptospira
possible with protein subunit vaccines?
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With complete bacterial genome sequences now available, "reverse vaccinology" can be conducted to identify proteins that can funct...
Wednesday, March 13, 2013
Triggering OspC production in
Borrelia burgdorferi
during tick feeding: Is temperature the real signal?
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The Ixodes tick, the vector of the Lyme disease spirochete, goes months without a meal. During this time, the Borrelia burgdorferi spiroc...
Tuesday, February 19, 2013
Is the major outer membrane lipoprotein LipL32 really exposed on the surface of
Leptospira
?
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Here's a study that may come as a surprise to those in the leptospirosis field. The outer membrane lipoprotein LipL32 is believed to be...
Monday, February 4, 2013
An autoantigen targeted during Lyme arthritis
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Infection by the spirochete Borrelia burgdorferi , if left untreated, can lead to a form of Lyme disease called Lyme arthritis. About 10% o...
Monday, January 14, 2013
LigB of
Leptospira interrogans
: Avoiding or exploiting complement?
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LigB has turned out to be a versatile surface protein for Leptospira interrogans . The protein is one of several that the spirochete uses t...
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