Spirochetes Unwound

Blogging about those twisty bacteria known as spirochetes

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Sunday, February 20, 2011

Another reason not to own a pet rat

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A pair of European doctors wrote about the trials of a 37-year-old man who came down with Weil's disease, a severe form of leptospirosis...
Tuesday, February 15, 2011

The quest for outer membrane proteins of the stealth pathogen Treponema pallidum: the cliffhanger episode

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Syphilis patients are able to generate antibodies against the spirochete Treponema pallidum .  However, if you were to mix sera from these p...
Saturday, January 1, 2011

Designing a Lyme disease vaccine to attack the tick vector

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Conventional vaccines target the surface components or secreted toxins of pathogens.  Erol Fikrig's group at Yale University has been ex...
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Sunday, November 28, 2010

How bacteria sort their lipoproteins (Lol!)

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Bacterial lipoproteins are proteins with covalently-attached lipid molecules that anchor the protein to the cytoplasmic or outer membrane.  ...
Sunday, August 1, 2010

The major outer membrane protein of Leptospira interrogans: Not essential for infection?

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Because leptospirosis is a potentially fatal disease, it would be worthwhile to figure out which of the many genes on the two chromosomes of...
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