Spirochetes Unwound

Blogging about those twisty bacteria known as spirochetes

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Saturday, July 24, 2010

Antigen presentation in the bloodstream: How invariant NKT cells are activated by Lyme disease spirochetes

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The spirochete Borrelia burgdorferi is the tick-borne agent of Lyme disease, which affects the joints, nervous system, and heart.  After ...
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Tuesday, June 22, 2010

Congenital syphilis, upward trend (again) in the United States

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Syphilis can be deadly if passed from an infected mother to her unborn child. The most recent CDC data show that 6.5% of U.S. infants with c...
Friday, April 30, 2010

Healthy human carriers of the spirochete Leptospira in the Peruvian Amazon

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The spirochete Leptospira is the agent of leptospirosis, a zoonosis that primarily burdens tropical regions of the world.  Moist condition...
Wednesday, March 31, 2010

A fresh approach towards a Lyme disease vaccine: targeting the tick

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We tend to focus on the pathogen when thinking about how the immune system responds to tick-borne infections.  Ticks also provoke an immune ...
Saturday, March 20, 2010

Tigecycline fails to eradicate persisting Borrelia burgdorferi

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Antibiotics are usually successful in treating Lyme disease, especially if administered early.  The problem is that some patients continue t...
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