Spirochetes Unwound

Neutrophils are the most abundant white blood cells in the bloodstream.  As the first immune cells to be recruited to infected tissues, they...

A massive study describing the genomes of 20 species of Leptospira was published a few weeks ago in PLOS Neglected Tropical Diseases .  Th...

A group at the Pasteur Institute succeeded in generating a bioluminescent strain of Leptospira interrogans .  Their study was published las...

I saw this video over at the Worms & Germs blog.  It's a new take on a popular Christmas carol.  Enjoy! Lyrics On the twelfth ...

In my previous post, I described the failure of researchers to come up with a conventional protein-based subunit vaccine that confers steril...

With complete bacterial genome sequences now available, "reverse vaccinology" can be conducted to identify proteins that can funct...

Here's a study that may come as a surprise to those in the leptospirosis field.  The outer membrane lipoprotein LipL32 is believed to be...

LigB has turned out to be a versatile surface protein for Leptospira interrogans .  The protein is one of several that the spirochete uses t...

Here are some of my favorite spirochete papers from 2012.  Direct access to all research articles (some behind a paywall) is provided via th...

The microscopic agglutination test (MAT) is designated the "gold standard" for the laboratory diagnosis of leptospirosis, a spiroc...

Scientists have demonstrated that a new attenuated leptospirosis vaccine protects laboratory hamsters from being killed by Leptospira , even...