Spirochetes Unwound

Thiamine, or vitamin B1, is vital for the survival of all living things.  One of the biologically functional forms of thiamine, thiamine pyr...

As a follow up to my previous post , I would like to say something about several mouse studies from Stephen Barthold's group.  These pap...

The bite of an infected Ixodes hard tick transmits the Lyme disease spirochete, Borrelia burgdorferi , to humans.  Ticks acquire B. burgdor...

Microbial pathogens that cause systemic infections often travel within the circulatory system to spread throughout the host.  Eventually, th...

The Ixodes tick, the vector of the Lyme disease spirochete, goes months without a meal.  During this time, the Borrelia burgdorferi spiroc...

Infection by the spirochete Borrelia burgdorferi , if left untreated, can lead to a form of Lyme disease called Lyme arthritis.  About 10% o...

Here are some of my favorite spirochete papers from 2012.  Direct access to all research articles (some behind a paywall) is provided via th...

Thanks to a recent study published in PLoS One , we now know that free-swimming Borrelia burgdorferi are able to organize themselves into ...

According to the CDC, 10-20% of Lyme disease patients who have completed antibiotic therapy continue to suffer from symptoms such as joint,...

The alternative sigma factor RpoS is a key player in the life cycle of Borrelia burgdorferi , the Lyme disease spirochete.  RpoS directs RNA...